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OIT Publications

 

OIT centered articles. 


Children who were treated with oral immunotherapy for cows' milk allergy showed long-term desensitisation seven years later. Acta Paediatr. 2016 Feb;105(2):215-9.

Clinical and laboratory 2-year outcome of oral immunotherapy in patients with cow's milk allergy. Allergy. 2016 Feb;71(2):275-8.

Oral Immunotherapy for Food Allergy. Immunol Allergy Clin North Am. 2016 Feb;36(1):55-69.

Advances in the Treatment of Food Allergy: Sublingual and Epicutaneous Immunotherapy. Immunol Allergy Clin North Am. 2016 Feb;36(1):39-54.

Oral Immunotherapy for Peanut Allergy. Annu Rev Med. 2016 Jan 14;67:375-85.

Differential response in allergen-specific IgE, IgGs and IgA levels for predicting outcome of oral immunotherapy. Pediatr Allergy Immunol. 2016 Jan 13.

Patient quality of life following induction of oral immunotherapy for food allergy. Pediatr Allergy Immunol. 2015 Dec 17.

Early sustained unresponsiveness after short-course egg oral immunotherapy: a randomized controlled study in
egg-allergic children. Clin Exp Allergy. 2015 Dec;45(12):1833-43.

Innate and adaptive dendritic cell responses to immunotherapy. Curr Opin Allergy Clin Immunol. 2015
Dec;15(6):575-80.

Efficacy of baked milk oral immunotherapy in baked milk-reactive allergic patients. J Allergy Clin Immunol. 2015 Dec;136(6):1601-6.

Randomized controlled trial of primary prevention of atopy using house dust mite allergen oral immunotherapy in
early childhood. J Allergy Clin Immunol. 2015 Dec;136(6):1541-1547.e11.

Food Allergy in childhood: phenotypes,prevention and treatment. Pediatr Allergy Immunol. 2015 Dec;26(8):711-20.

Improving the safety of oral immunotherapy for food allergy. Pediatr Allergy Immunol. 2015 Nov 23.

Half of the children who received oral immunotherapy for a cows' milk allergy consumed milk freely after 2.5 years. Acta Paediatr. 2015 Nov;104(11):1164-8.

Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial: a critical appraisal.Br J Dermatol. 2015 Nov;173(5):1129-30.

Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial: a critical appraisal. Br J Dermatol. 2015 Nov;173(5):1125-9.

A randomized, double-blind, placebo-controlled study of omalizumab combined with oral immunotherapy for the treatment of cow's milk allergy. J Allergy Clin Immunol. 2015 Oct 30. pii: S0091-6749(15)01438-4.

High IgE levels to α-lactalbumin, β-lactoglobulin and casein predict less successful cow's milk oral immunotherapy. Allergy. 2015 Aug;70(8):955-62.

Modulation of Peanut-specific humoral and cellular responses pre-and post-oral immunotherapy. Clin Exp Allergy. 2015 Jul;45(7):1146-9.

 Analysis of cytokine production by peanut-reactive T cells identifies residual Th2 effectors in highly allergic
children who received peanut oral immunotherapy. Clin Exp Allergy. 2015Jul;45(7):1201-13.

Peanut oral immunotherapy transiently expands circulating Ara h 2-specific B cells with a homologous repertoire in unrelated subjects. J Allergy Clin Immunol. 2015 Jul;136(1):125-134.e12.

Oral Immunotherapy for Egg Allergy: A Double-Blind Placebo-Controlled Study, with Postdesensitization Follow-Up. J Allergy Clin Immunol Pract. 2015 Jul-Aug;3(4):532-9.

Clinical efficacy and immunological changes subjacent to egg oral immunotherapy. Ann Allergy Asthma Immunol. 2015 Jun;114(6):504-9.

Identification of novel peptide biomarkers to predict safety and efficacy of cow's milk oral immunotherapy by
peptide microarray. Clin Exp Allergy. 2015 Jun;45(6):1071-84. doi: 10.1111/cea.12528. PubMed PMID: 25772539.

Oral Immunotherapy for Peanut Allergy. Annu Rev Med. 2015 Aug 26. [Epub ahead of print]

Wheat oral immunotherapy for wheat-induced anaphylaxis. J Allergy Clin Immunol. 2015 Aug 26. pii: S0091-6749(15)01024-6.

Does clinical protection persist after food allergen oral immunotherapy? Immunotherapy. 2015 Aug 28. [Epub ahead of print] No abstract available.

Early Sustained Unresponsiveness After Short-course Egg Oral Immunotherapy: a Randomized Controlled Study in Egg Allergic Children. Clin Exp Allergy. 2015 Aug 3.

Efficacy of baked milk oral immunotherapy in baked milk-reactive allergic patients. J Allergy Clin Immunol. 2015 Jul 17. pii: S0091-6749(15)00794-0.

Half of the children who received oral immunotherapy for a cows' milk allergy consumed milk freely after 2.5 years. Acta Paediatr. 2015 Jul 20.

Oral immunotherapy and anti-IgE antibody treatment for food allergy. World Allergy Organ J. 2015 Jul 6;8(1):20.

Oral immunotherapy for food allergy: towards a new horizon. Allergy Asthma Immunol Res. 2013 Jan;5(1):3-15.

Food specific oral immunotherapy: a potential treatment for food allergy. Expert Rev Gastroenterol Hepatol. 2015 Sep;9(9):1147-59.

Successful desensitization in a boy with severe cow's milk allergy by a combination therapy using omalizumab and rush oral immunotherapy. Allergy Asthma Clin Immunol. 2015 May 28;11(1):18.

Oral immunotherapy and potential treatment. Chem Immunol Allergy. 2015;101:106-13.

High IgE levels to α-lactalbumin, β-lactoglobulin and casein predict less successful cow's milk oral immunotherapy. Allergy. 2015 Aug;70(8):955-62. doi: 10.1111/all.12647. Epub 2015 May 28.

A Web site-based reporting system for monitoring home treatment during oral immunotherapy for food allergy. Ann Allergy Asthma Immunol. 2015 Jun;114(6):510-5. doi: 10.1016/j.anai.2015.04.007. Epub 2015 May 1.

Clinical efficacy and immunological changes subjacent to egg oral immunotherapy. Ann Allergy Asthma Immunol. 2015

Analysis of cytokine production by peanut-reactive T cells identifies residual Th2 effectors in highly allergic children who received peanut oral immunotherapy. Clin Exp Allergy. 2015 Jul;45(7):1201-13.

Identification of novel peptide biomarkers to predict safety and efficacy of cow's milk oral immunotherapy by peptide microarray.

Martínez-Botas J, Rodríguez-Álvarez M, Cerecedo I, Vlaicu C, Diéguez MC, Gómez-Coronado D, Fernández-Rivas M, de la Hoz B.

Clin Exp Allergy. 2015 Jun;45(6):1071-84. doi: 10.1111/cea.12528.

Oral Immunotherapy for Egg Allergy: A Double-Blind Placebo-Controlled Study, with Postdesensitization Follow-Up. J Allergy Clin Immunol Pract. 2015 Jul-Aug;3(4):532-9.

Oral and sublingual immunotherapy for food allergy. World Allergy Organ J. 2014 Dec 8;7(1):35.

Study of induction of Tolerance to Oral Peanut: a randomised controlled trial of desensitisation using peanut oral immunotherapy in children (STOP II). Southampton (UK): NIHR Journals Library; 2014 Dec.

Administration of a probiotic with peanut oral immunotherapy: A randomized trial. J Allergy Clin Immunol. 2015 Mar;135(3):737-44.e8.

Allergist-reported trends in the practice of food allergen oral immunotherapy. J Allergy Clin Immunol Pract. 2015 Jan-Feb;3(1):33-8.

Suppression of the immunologic response to peanut during immunotherapy is often transient. J Allergy Clin Immunol. 2015 May;135(5):1283-92.

A randomized, double-blind, placebo-controlled pilot study of sublingual versus oral immunotherapy for the treatment of peanut allergy. J Allergy Clin Immunol. 2015 May;135(5):1275-82.e1-6.

Oral immunotherapy for the treatment of food allergy. Hum Vaccin Immunother. 2014;10(8):2295-302.

Oral and sublingual immunotherapy for egg allergy. Cochrane Database Syst Rev. 2014 Nov 18;11:CD010638.

Safety and efficacy profile and immunological changes associated with oral immunotherapy for IgE-mediated cow's milk allergy in children: systematic review and meta-analysis. J Investig Allergol Clin Immunol. 2014;24(5):298-307. Review.

Sublingual (SLIT) versus oral immunotherapy (OIT) for food allergy. Curr Allergy Asthma Rep. 2014 Dec;14(12):486.
Oral immunotherapy in children with IgE-mediated wheat allergy: outcome and molecular changes. J Investig Allergol Clin Immunol. 2014;24(4):240-8.

Relation between eosinophilic esophagitis and oral immunotherapy for food allergy: a systematic review with meta-analysis. Ann Allergy Asthma Immunol. 2014 Dec;113(6):624-9.

Modulation of dendritic cell innate and adaptive immune functions by oral and sublingual immunotherapy. Clin Immunol. 2014 Nov;155(1):47-59.

Successful wheat-specific oral immunotherapy in highly sensitive individuals with a novel multirush/maintenance regimen. Asia Pac Allergy. 2014 Jul;4(3):180-3.

Oral immunotherapy induces IgG antibodies that act through FcγRIIb to suppress IgE-mediated hypersensitivity. J Allergy Clin Immunol. 2014 Dec;134(6):1310-1317.e6.

Effect of ketotifen premedication on adverse reactions during peanut oral immunotherapy. Allergy Asthma Clin Immunol. 2014 Jul 9;10(1):36.

Effect of ketotifen premedication on adverse reactions during peanut oral immunotherapy. Allergy Asthma Clin Immunol. 2014 Jul 9;10(1):36.

Food allergy and the oral immunotherapy approach. Arch Immunol Ther Exp (Warsz). 2015 Feb;63(1):31-9.
Oral Immunotherapy for Treatment of Immunoglobulin E-Mediated Food Allergy: The Transition to Clinical Practice. Pediatr Allergy Immunol Pulmonol. 2014 Jun 1;27(2):42-50. Review.

Monitoring Ara h 1, 2 and 3-sIgE and sIgG4 antibodies in peanut allergic children receiving oral rush immunotherapy. Pediatr Allergy Immunol. 2014 Jun;25(4):323-8.

Clinical studies in oral allergen-specific immunotherapy: differences among allergens. Int Arch Allergy Immunol. 2014;164(1):1-9.

Multiple-allergen oral immunotherapy improves quality of life in caregivers of food-allergic pediatric subjects. Allergy Asthma Clin Immunol. 2014 May 12;10(1):25.

Specific antibodies in oral immunotherapy for cow's milk allergy: kinetics and prediction of clinical outcome. Int Arch Allergy Immunol. 2014;164(1):32-9.

Efficacy of allergen-specific immunotherapy for peanut allergy: a meta-analysis of randomized controlled trials. Allergy Asthma Proc. 2014 Mar-Apr;35(2):171-7.

 Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3). J Allergy Clin Immunol. 2014 Feb;133(2):500-10.

Oral immunotherapy for peanut allergy: multipractice experience with epinephrine-treated reactions. J Allergy Clin Immunol Pract. 2014 Jan-Feb;2(1):91-6.

Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomized controlled trial. Lancet. 2014 Apr 12;383(9925):1297-304.

Safety and feasibility of oral immunotherapy to multiple allergens for food allergy. Allergy Asthma Clin Immunol. 2014 Jan 15;10(1):1.

Use of IgE and IgG4 epitope binding to predict the outcome of oral immunotherapy in cow's milk allergy. Pediatr Allergy Immunol. 2014 May;25(3):227-35.

Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy. J Allergy Clin Immunol. 2014 Feb;133(2):468-75.

Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomized controlled trial. Lancet. 2014 Apr 12;383(9925):1297-304. doi: 10.1016/S0140-6736(13)62301-6. Epub 2014 Jan 30.

Immunotherapy for peanut allergy: A meta-analysis of randomized controlled trials. Allergy Asthma Proc. 2014 Mar;35(2):171-7. doi: 10.2500/aap.2014.35.3730.

Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3).J Allergy Clin Immunol. 2014 Feb;133(2):500-510.e11. doi: 10.1016/j.jaci.2013.12.1037.

Phase 1 results of safety and tolerability in a rush oral immunotherapy protocol to multiple foods using Omalizumab.  Allergy Asthma Clin Immunol. 2014 Feb 20;10(1):7. doi: 10.1186/1710-1492-10-7.

Oral immunotherapy for peanut allergy: multipractice experience with epinephrine-treated reactions. J Allergy Clin Immunol Pract. 2014 Jan-Feb;2(1):91-6. doi: 10.1016/j.jaip.2013.10.001.

Safety and feasibility of oral immunotherapy to multiple allergens for food allergy. Allergy Asthma Clin Immunol. 2014 Jan 15;10(1):1

New efficacy of LTRAs (montelukast sodium): it possibly prevents food-induced abdominal symptoms during oral immunotherapy. Allergy Asthma Clin Immunol. 2014 Jan 17;10(1):3. doi: 10.1186/1710-1492-10-3

Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial, Lancet. Early Online Publication, 30 January 2014

Effectiveness and safety of orally administered immunotherapy for food allergies: a systematic review and meta-analysis. Br J Nutr. 2014 Jan;111(1):12-22.

Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy. J Allergy Clin Immunol. 2013 Dec 19.

Increased cow's milk protein-specific IgG4 levels after oral desensitization in 7- to 12-month-old infants. Ann Allergy Asthma Immunol. 2013 Dec;111(6):523-8

Oral and sublingual immunotherapy for food allergy. Asian Pac J Allergy Immunol. 2013 Sep;31(3):198-209.

Oral immunotherapy and tolerance induction in childhood. Pediatr Allergy Immunol. 2013 Sep;24(6):512-20. doi: 10.1111/pai.12100. Epub 2013 Aug 2.

Effectiveness and safety of orally administered immunotherapy for food allergies: a systematic review and meta-analysis. Br J Nutr. 2013 Aug 15:1-11.

Oral immunotherapy for peanut allergy in clinical practice is ready. Allergy Asthma Proc. 2013 May-Jun;34(3):205-9

Sublingual immunotherapy for peanut allergy: a randomized, double-blind, placebo-controlled multicenter trial. Journal of Allergy and Clinical Immunology DOI: 10.1016/j.jaci.2012.11.011 (2013)

Oral food desensitization in children with IgE-mediated hen's egg allergy: a new protocol with raw hen's egg. Pediatr Allergy Immunol. 2013 Feb;24(1):75-83. doi: 10.1111/j.1399-3038.2012.01341.x. Epub 2012 Aug 13.

Milk oral immunotherapy is effective in school-aged children. Acta Paediatr. 2013 Feb;102(2):172-6. doi: 10.1111/j.1651-2227.2012.02815.x. Epub 2012 Sep 7.

Oral immunotherapy for food allergy: towards a new horizon. Allergy Asthma Immunol Res. 2013 Jan;5(1):3-15. doi: 10.4168/aair.2013.5.1.3. Epub 2012 Nov 28.

Peanut oral immunotherapy modifies IgE and IgG4 responses to major peanut allergens. Allergy Clin Immunol. 2013 Jan;131(1):128-34.e1-3. doi: 10.1016/j.jaci.2012.10.048. Epub 2012 Nov 27.

Oral immunotherapy in hen's egg-allergic children increases a hypo-proliferative subset of CD4+ T cells that could constitute a marker of tolerance achievement. Pediatr Allergy Immunol. 2012 Nov;23(7):648-53. doi: 10.1111/j.1399-3038.2012.01333.x. Epub 2012 Jul 26.

**Effect of oral immunotherapy to peanut on food-specific quality of life. Ann Allergy Asthma Immunol. 2012 Nov;109(5):348-352

Evidence of pathway-specific basophil anergy induced by peanut oral immunotherapy in peanut-allergic children. Clin Exp Allergy. 2012 Aug;42(8):1197-205

Oral immunotherapy for food allergy: Clinical and preclinical studies. Adv Drug Deliv Rev. 2012 Oct 22. pii: S0169-409X(12)00322-5

Allergen-specific oral immunotherapy for peanut allergy. Cochrane Database Syst Rev. 2012 Sep 12;9

Oral immunotherapy induces local protective mechanisms in the gastrointestinal mucosa. J Allergy Clin Immunol. 2012 Jun;129(6):1579-1587

Impact of oral immunotherapy on quality of life in children with cow milk allergy: a pilot study.Int J Immunopathol Pharmacol. 2012 Jul-Sep;25(3):793-8.

Oral immunotherapy for cow's milk allergy. Current Opinion in Allergy & Clinical Immunology. 12(3):271-7, 2012 Jun

The Safety of Peanut Oral Immunotherapy in Peanut-Allergic Subjects in a Single-Center Trial. Int Arch Allergy Immunol. 2012 Jun 1;159(2):179-182.

Egg oral immunotherapy. Current Opinion in Allergy & Clinical Immunology. 12(3):278-82, 2012 Jun

Oral immunotherapy induces local protective mechanisms in the gastrointestinal mucosa.
J Allergy Clin Immunol. 2012 Jun;129(6):1579-1587

Allergy to goat's and sheep's milk in a population of cow's milk-allergic children treated with oral immunotherapy. Pediatric Allergy & Immunology. 23(2):128-32, 2012 Mar

Oral immunotherapy for the treatment of peanut allergy: systematic review of six case series studies. Primary Care Respiratory Journal. 21(1):41-9, 2012 Mar

Oral immunotherapy for IgE-mediated cow's milk allergy: a systematic review and meta-analysis. Clinical & Experimental Allergy. 42(3):363-74, 2012 Mar

The safety and efficacy of sublingual and oral immunotherapy for milk allergy. Journal of Allergy & Clinical Immunology. 129(2):448-55, 455.e1-5, 2012 Feb

Adverse effects during specific oral tolerance induction: in home phase. Allergologia et Immunopathologia. 40(1):41-50, 2012 Jan-Feb.

Oral immunotherapy for the treatment of food allergy. Isr Med Assoc J. 2012 Jan;14(1):63-9.

Immunology in the Clinic Review Series; focus on allergies: immunotherapy for food allergy. Clin Exp Immunol. 2012 Jan;167(1):26-31.
 
Efficacy and safety of high-dose peanut oral immunotherapy with factors predicting outcome. Clinical & Experimental Allergy. 41(9):1273-81, 2011 Sep

Oral Desensitization for Food Hypersensitivity. Immunol Allergy Clin N Am 31 (2011) 367–376.

A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response. Journal of Allergy & Clinical Immunology. 127(3):654-60, 2011 Mar

A randomized controlled study of peanut oral immunotherapy: clinical desensitization and modulation of the allergic response. Journal of Allergy & Clinical Immunology. 127(3):654-60, 2011 Mar

Office-based oral immunotherapy for food allergy is safe and effective. Journal of Allergy & Clinical Immunology. 127(1):290-1Individualized IgE-based dosing of egg oral immunotherapy and the development of tolerance. Annals of Allergy, Asthma, & Immunology. 105(6):444-50, 2010 Dec

Oral immunotherapy for cow's milk allergy with a weekly up-dosing regimen: a randomized single-blind controlled study.
Annals of Allergy, Asthma, & Immunology. 105(5):376-81, 2010 Nov

Oral peanut immunotherapy in children with peanut anaphylaxis.
Journal of Allergy & Clinical Immunology. 126(1):83-91.e1, 2010 Jul

Is oral immunotherapy the cure for food allergies?. [Review] [26 refs] 
Current Opinion in Allergy & Clinical Immunology. 10(3):214-9, 2010 Jun

Specific oral tolerance induction (SOTI) in pediatric age: clinical research or just routine practice?Pediatr Allergy Immunol. 2010 Mar;21(2 Pt 2):e446-9. Epub 2009 Jul 2.

Adverse reactions during peanut oral immunotherapy home dosing. 
Journal of Allergy & Clinical Immunology. 124(6):1351-2, 2009 Dec

Clinical efficacy and immune regulation with peanut oral immunotherapy.
Journal of Allergy & Clinical Immunology. 124(2):292-300, 300.e1-97, 2009 Aug

Safety of a peanut oral immunotherapy protocol in children with peanut allergy.
Journal of Allergy & Clinical Immunology. 124(2):286-91, 291.e1-6, 2009 Aug

Successful oral tolerance induction in severe peanut allergy. Allergy. 64(8):1218-20, 2009 Aug

A randomized, double-blind, placebo-controlled study of milk oral immunotherapy for cow's milk allergy.
Journal of Allergy & Clinical Immunology. 122(6):1154-60, 2008 Dec 

Egg oral immunotherapy in nonanaphylactic children with egg allergy.
Journal of Allergy & Clinical Immunology. 119(1):199-205, 2007 Jan.

Oral desensitization with food is food-specific and protein-specific.
International Journal of Immunopathology & Pharmacology. 24(3):803-11, 2011 Jul-Sep.

Oral specific desensitization in food-allergic children. Digestive Diseases & Sciences. 52(7):1662-72, 2007 Jul.

Sublingual immunotherapy for hazelnut food allergy: A randomized, double-blind, placebo-controlled study with a standardized hazelnut extract, J. Allergy Clin Immunol 2005; 116:1073-9.

Oral desensitizing treatment in food allergy: clinical and immunological results.[Erratum appears in Aliment Pharmacol Ther. 2003 May 1;17(9):1205] Alimentary Pharmacology & Therapeutics. 17(3):459-65, 2003 Feb

Food allergy in children: results of a standardized protocol for oral desensitization.
Hepato-Gastroenterology. 45(19):52-8, 1998 Jan-Feb.

Oral specific hyposensitization in the management of patients allergic to food.
Allergologia et Immunopathologia. 12(4):275-81, 1984 Jul-Aug.

Intolerance of beta-lactoglobulin with anaphylactic shock ameliorated by desensitization]. [French]
Pediatrie. 24(5):585-95, 1969 Jul-Aug.

Typical milk-egg albumen allergy and its desensitization therapy]. [Japanese]
Nippon Ishikai Zasshi - Journal of the Japan Medical Association. 59(12):1579-86, 1968 Jul
 
ORAL DESENSITIZATION IN FOOD ALLERGY.  Can Med Assoc J. 1940 Sep;43(3):234-6. No abstract available

A case of egg poisoning. Lancet 1908;1:716 (first journal article on OIT)

 

 

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